Zinc intoxication has recently emerged as an important clinical cause of disease in birds. Zinc is an essential micronutrient and is important in many metabolic activities and for proper functioning of the immune system. However, when birds ingest zinc at high levels, zinc is a potential toxin.

The metal rich environments that birds live in and bird's predisposition for chewing on these environments have put birds at risk. Galvanized wire cages may result in zinc being available for ingestion. The preferred type of galvanized wire, called Tinsley wire, is galvanized after welding and is generally considered safe. However, recent wire imports from China and Eastern Europe may not be as safe. Powder coated cages are widely available. Most are made from wrought iron or rolled steel wire and are then baked to harden the finish. Some powder formulas contain zinc. Zinc is not essential for the process but can be added to speed curing or harden the finish. It is estimated that 1 - 2% of powder coated cages contain added zinc. Zinc quick links are often used to attach toys. Galvanized dishes and cup holders may release zinc into food and water. Stainless steel nuts, screws, quick links, and dishes should be used to replace suspect products.

Clinical signs of zinc intoxication are nonspecific. They may range from feather destruction to gastrointestinal discomfort or general listlessness. At high doses birds may seizure or develop fatal anemia. Zinc toxicosis can be slow and insidious. Birds frequently do not become ill immediately after exposure to a new cage or toy. Days, weeks, or months of chewing may occur before clinical signs become apparent.